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. Joseph P, et al.Lancet. 2021 Aug 27:S0140-6736(21)01827-4. doi: 10.1016/S0140-6736(21)01827-4. Online ahead of print.Lancet. 2021.PMID: 34469765.
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Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial.
Chow CK, Atkins ER, Hillis GS, Nelson MR, Reid CM, Schlaich MP, Hay P, Rogers K, Billot L, Burke M, Chalmers J, Neal B, Patel A, Usherwood T, Webster R, Rodgers A; QUARTET Investigators.